Bone tissue used as a filler in bone reconstruction as well as large bone segments are preserved at -800C.
After processing, tissues are preserved at - 800C without the use of cryopreservants, thereby eliminating cell components that could cause adverse recipient reactions on implantation.
Frozen bank bone maintains the following properties:
- Osteoinduction: the ability to make new bone by activating the mesenchymal cells in the surrounding host tissue and their transformation into bone producing osteoblasts. This process is connected to the presence of growth factors, essentially bone morphogenetic proteins (BMP);
- Osteoconduction: the transplant / graft acts as a passive three-dimensional structure, or scaffold, that facilitates the infiltration of blood vessels and the formation of new bone;
- Excellent resistance to bacterial infections;
- The absence of immunogenicity.