When it is unnecessary for tissues to retain their cell vitality, they can be stored frozen at -80°C. The freezing  procedure involves suitably packaging each type of tissue and identifying it for traceability purposes. Non-vital tissues are kept frozen at -80°C without any added cryopreserving agents.

These frozen tissues nonetheless retain the following features:

• osteoinduction: the synthesis of new bone involves the activation of the host’s mesenchymal cells by the surrounding tissue and their subsequent transformation into osteoblasts, which form new bone. This process relies on the presence of growth factors, and particularly BMP (bone morphogenetic proteins), in the transplant/graft;
• osteoconduction: the transplant/graft serves as a three-dimensional passive scaffold that facilitates the passage of blood vessels and the formation of new bone.

Excellent resistance to bacterial infections

No immunogenicity (and no risk of rejection)